Alexandra Mark-Schwarz

Alexandra Mark-Schwarz, Ph.D.,

Dozentin

Naturwissenschaft, Bioethik, Akademie und Schule, Öffentlichkeitsarbeit

 

Zur Person

1998-2004 Studium der Biologie an der Rheinischen Friedrich-Wilhelms-Universität Bonn

2009 Promotion in Biologie (Parasitologie) an der University of Aberdeen, Schottland, Dissertationsthema: Antibody responses to saliva of the Chagas disease vector Triatoma infestans (Hemiptera: Reduviidae): Potential novel epidemiological tools for Chagas disease surveillance

2006-2012 Projektarbeiten als wissenschaftliche Mitarbeiterin in den USA und Südamerika (Peru, Bolivien und Argentinien)

2010-2014 Wissenschaftliche Angestellte an der Academy of Sciences of the Czech Republic, Budweis, Tschechien

Seit 2014 Dozentin an der Bischöflichen Akademie des Bistums Aachen


Arbeitsschwerpunkte

Naturwissenschaft, Bioethik, Akademie und Schule, Öffentlichkeitsarbeit

 

  • Schwarz, A., Maier, W. A., Kampen, H. A GIS-based study on the population dynamics of Ixodes ricinus in the Siebengebirge near Bonn. Int. J. Med. Microbiol. Suppl. 293 (Suppl. 38), 56, (2004).

  • Assumpcao, T. C. F., Francischetti, I. M. B., Andersen, J. F., Schwarz, A., Santana, J. M., Ribeiro, J. M. C. An insight into the sialome of the blood sucking bug, Triatoma infestans. Insect. Biochem. Mol. Biol. 38, 213-232, (2008).

  • Schwarz, A., Maier, W. A., Kistemann, T., Kampen, H. Analysis of the distribution of the tick Ixodes ricinus L. (Acari: Ixodidae) in a nature reserve of western Germany using Geographic Information Systems. Int. J. Hyg. Environ. Health. 212, 87-96, (2009).

  • Schwarz, A., Sternberg, J. M., Johnston, V., Medrano-Mercado, N., Anderson, J. M., Hume, J. C. C., Valenzuela, J. G., Schaub, G. A., Billingsley, P. F. Antibody responses of domestic animals to salivary antigens of Triatoma infestans as biomarkers for low-level infestation of triatomines. Int. J. Parasitol. Int. J. Parasitol. 39, 1021-1029, (2009).

  • Schwarz, A., Helling, S., Collin, N., Teixeira, C. R., Medrano-Mercado, N. , Hume, J. C. C., Assumpção, T. C., Marcus, K., Stephan, C., Meyer, H. E., Ribeiro, J. M., Billingsley, P. F., Valenzuela, J. G., Sternberg, J. M., Schaub, G. A. Immunogenic salivary proteins of Triatoma infestans: Development of a recombinant antigen for the detection of low-level infestation of triatomines. PLoS Negl. Trop. Dis. 3, e532, (2009).

  • Schwarz, A., Medrano-Mercado, N., Billingsley, P. F., Schaub, G. A., Sternberg, J. M. IgM-antibody responses of chickens to salivary antigens of Triatoma infestans as early biomarkers for low-level infestation of triatomines. Int. J. Parasitol. 40, 1295-1302, (2010).

  • Schwarz, A., Ancca Juarez, J., Richards, J., Rath, B., Quispe Machaca, V., Castro, Y. E., Málaga, E. S., Levy, K., Gilman, R. H., Bern, C., Verastegui, M., Levy, M. Z. Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission. Int. J. Parasitol. 41, 591-594, (2011).

  • Schwarz, A., Valdés, J.J., Kotsyfakis, M. The role of cystatins in tick physiology and blood feeding. Ticks Tick Borne Dis. 3, 117-127, (2012).

  • Schwarz, A., Hönig, V., Vavrušková, Z., Grubhoffer, L., Balczun, C., Albring, A., Schaub, G. A. Abundance of Ixodes ricinus and prevalence of Borrelia burgdorferi s.l. in the nature reserve Siebengebirge, Germany, in comparison to three former studies from 1978 onwards. Parasit Vectors. 5, 268, (2012).

  • Valdés, J. J., Schwarz, A., Cabeza de Vaca, I., Calvo, E., Pedra, J. H., Guallar, V., Kotsyfakis, M. Tryptogalinin is a tick kunitz serine protease inhibitor with a unique intrinsic disorder. PLoS One 8, e62562, (2013).

  • Assumpção, T. C., Ma, D., Schwarz, A., Reiter, K., Santana, J. M., Andersen, J. F., Ribeiro, J. M., Nardone, G, Yu, L. L., Francischetti, I. M. Salivary antigen-5/CAP family members are Cu2+-dependent antioxidant enzymes that scavenge O2 and inhibit collagen-induced platelet aggregation and neutrophil oxidative burst. J Biol Chem. 288, 14341-14361, (2013).

  • Schwarz, A., von Reumont, B. M., Erhart, J., Chagas, A. C., Ribeiro, J. M. C., Kotsyfakis, M. De novo Ixodes ricinus salivary gland transcriptome analysis using two different next-generation sequencing methodologies. FASEB J. 27, 4745-4756, (2013).

  • Schwarz, A., Medrano-Mercado, N., Schaub, G. A., Struchiner, C. J., Bargues, M. D., Levy, M. Z., Ribeiro, J. M. An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations. PLoS Negl Trop Dis. 8, e3372, (2014).

  • Dorňáková, V., Salazar-Sanchez, R., Borrini-Mayori, K., Carrion-Navarro, O., Levy, M. Z., Schaub, G. A., Schwarz, A. Characterization of guinea pig antibody responses to salivary proteins of Triatoma infestans for the development of a triatomine exposure marker. PLoS Negl Trop Dis. 8, e2783, (2014).

  • Schwarz, A., Tenzer, S., Hackenberg, M., Erhart, J., Gerhold-Ay, A., Mazur, J., Kuharev, J., Ribeiro, J. M., Kotsyfakis, M. A systems level analysis reveals transcriptomic and proteomic complexity in ixodes ricinus midgut and salivary glands during early attachment and feeding. Mol Cell Proteomics. 13, 2725-35, (2014).

  • Schwarz, A., Cabezas-Cruz, A., Kopecký, J., Valdés, J. J. Understanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data. BMC Evol Biol. 14, 4, (2014).